8–12 Jul 2025
Politechnica Univ
Europe/Bucharest timezone

Perspectives on Breast Cancer Diagnosis Assisted by Convolutional Neural Networks Applied to High-Sensitivity Talbot-Lau Interferometric Imaging

10 Jul 2025, 12:30
15m
Politechnica Univ

Politechnica Univ

Splaiul Independenței 313, București 060042
Oral Presentations S02 – Biophysics, Life Sciences, Medical Physics Biophysics, Life Sciences, Medical Physics

Speaker

Ionuț-Cristian Ciobanu (Horia Hulubei National Institute for Physics and Nuclear Engineering)

Description

Early detection of breast cancer remains a crucial objective in modern medicine. High-sensitive X-ray imaging based on Talbot-Lau interferometry offers enhanced soft-tissue contrast compared to conventional mammography, making it a promising tool for non-invasive diagnostics. This work explores the integration of Convolutional Neural Networks (CNNs) with high-sensitivity Talbot-Lau imaging to support and improve automatic tumor detection.
We propose a methodological approach consisting of three parts: pre-processing and filtering of raw images to enhance the contrast-to-noise ratio (CNR); classification of scattering images using a ResNet50 model to distinguish between tumors, calcifications, and fibrous tissue; and a precise segmentation of tumor regions using a U-Net architecture.
Experimental results demonstrate a significant improvement in both detection accuracy and lesion localization. These findings highlight the considerable potential of integrating advanced phase-contrast imaging with deep learning techniques as a possible decision-support tool for breast cancer screening and diagnosis.

Primary author

Ionuț-Cristian Ciobanu (Horia Hulubei National Institute for Physics and Nuclear Engineering)

Co-authors

Dan Stutman (Extreme Light Infrastructure – Nuclear Physics, Magurele, Romania) Elena Anghel (Extreme Light Infrastructure – Nuclear Physics, Magurele, Romania) Nicoleta Safca (Extreme Light Infrastructure – Nuclear Physics, Magurele, Romania)

Presentation materials

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